Crucial revision of the manuscript for important intellectual content: SW?and?XW. it is unlikely due to reinfections with SARS\CoV\2 viruses. Those patients with recurrent positive SARS\CoV\2 most likely never fully cleared the computer virus from their systems. Whether they will eventually eradicate the computer TC-G-1008 virus is to be studied. The possibility of chronic contamination with SARS\CoV\2 could not be ruled out and should be closely monitored. Actually, it reported that over 30 cases of patients infected with SARS\CoV\2 were never able to clear the computer virus and were still positive for the computer virus 2 to 3 3 months after initial infection, according to the National Health Commission rate, China. SARS\CoV\2 computer virus was detected in the throat swabs, which strongly suggests that those patients Zfp622 can still shed SARS\CoV\2 computer virus 6 and are infectious. Additionally, those patients all had IgG antibodies to SARS\CoV\2, which casts doubts on the protective role of IgG antibodies against this virus and the validity of using positive IgG test results as an immune certificate for COVID\19. Our findings suggest that some of those with positive IgG test results may be tested positive again for SARS\CoV\2 in their throat swabs and thus infectious after two consecutive unfavorable assessments for SARS\CoV\2. These findings have important implications for public health and management of recovered patients with COVID\19 around the world. CONFLICT OF INTERESTS The authors declare that there are no conflict of interests. AUTHOR CONTRIBUTIONS XW?had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. TL, SW,?and GZ?contributed equally to the study. XW, FG,?and YL?contributed equally as senior authors. Concept and design: TL, SW,?and GZ. Acquisition, analysis, or interpretation of data: TL, SW,?GZ, and FZ. Drafting of the manuscript: TL, SW, FG, and XW. Crucial revision of the manuscript for important intellectual content: SW?and?XW. Statistical analysis: TL and?FG. Supporting information Supplementary information Click here for additional data file.(81K, docx) ACKNOWLEDGMENTS The part of the study was supported by National Key Research and Development Program of China (2020YFC0845500). The content is usually solely the responsibility of the authors and does not necessarily represent the official views TC-G-1008 of the sponsors. Notes Funding Information National Key Research and Development Program of China, Grant/Award Number: 2020YFC0845500 Tao Liu,?Sanyun Wu, and?Guang Zeng contributed equally as first authors to this work.?Yirong Li,?Fangjian Guo, and Xinghuan Wang contributed equally as senior authors to this work. Contributor TC-G-1008 Information Fangjian Guo, Email: ude.bmtu@ougaf. Xinghuan Wang, Email: nc.ude.uhw@nauhgnixgnaw. Recommendations 1. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727\733. [PMC free article] [PubMed] [Google Scholar] 2. Wang W, Xu Y, Gao R, et al. Detection of SARS\CoV\2 in different types of clinical specimens. JAMA. 2020. [PMC free article] [PubMed] [Google Scholar] 3. Lan L, Xu D, Ye G, et al. Positive RT\PCR test results in patients recovered from COVID\19. JAMA. 2020;323:1502. [PMC free article] [PubMed] [Google Scholar] 4. Li Z, Yi Y, Luo X, et al. Development and clinical application of a?rapid IgM\IgG combined antibody test for SARS\CoV\2 infection diagnosis. J Med Virol. 2020:jmv.25727. [PMC free article] [PubMed] [Google Scholar] 5. Zeng H. Department of Laboratory Medicine ZHoWU, Wuhan, China, Xu C, et al. Antibodies in infants born to mothers with COVID\19 pneumonia. JAMA. 2020. [PMC free article] [PubMed] [Google Scholar] 6. W?lfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID\2019. Nature. 2020;581:1\10. [PubMed] [Google Scholar].